Basic Research Sector Structural Biology Group

Group Introduction

Leader:
Professor Seizo Koshiba (INGEM)

This group contributes to the realization of Next-Generation medicine by developing drug discovery technologies based on the molecular structures of proteins. Using two Cryo-Electron Microscopes (transmission and scanning) and an 800MHz NMR, the group advances three-dimensional structural analysis and the functional elucidation of disease-related biomolecules. To date, the group has successfully resolved the structures of multiple proteins, such as ribosomes and membrane proteins, at resolutions of approximately 2-4Å. In addition to supporting drug discovery research by companies and universities, the group collaborates with various departments in INGEM.

Organization