Clinical and Translational Research Sector Clinical Phenome Group

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Group Introduction

Leader:
Professor Ritsuko Shimizu (Graduate School of Medicine)

This group conducts integrated multi-omics analyses to identify disease-related markers for diagnostics, treatment, and prevention. It also develops data platforms to assess disease susceptibility through metabolome, proteome, and microbiome profiling. By advancing metabolome and proteome analysis of biological samples, this group aims to apply these approaches to cancer type identification, treatment efficacy evaluation, and prognosis prediction. Additionally, the group is expanding the range of measurable metabolites and sample types to include non-cancer diseases. In parallel, ongoing projects focus on collecting metagenomic samples and analyzing temporal changes in the microbiome associated with diseases such as ovarian cancer, oral cancer, and brain tumors.

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Clinical Phenome Group Results

Main Results

  • 質量分析装置を用いたメタボロームおよびプロテオーム解析フローの構築
  • 各種婦人科がんに特徴的な血漿中代謝物プロファイルを特定し、論文公開
  • 腸内、口腔、腫瘍内等多様な微生物叢を対象としたメタゲノム解析の支援

Usage Guide

  • Cryo-Electron Microscope Usage Guide
  • Support for Disease Model Animal Generation and Analysis (Campus Only)
  • Biobank Cross Search (Campus Only)
  • Metabolome Analysis Support
  • Proteome Analysis Support
  • Metagenome Analysis Support

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