Basic Research Sector Genetic Variation Verification Group
Group Introduction
Leader:
Associate Professor Mikiko Suzuki (Graduate School of Medicine)
This group verifies the physiological and pathological significance of gene mutations and polymorphisms found in human specimens through the creation and analysis of genetically modified mice. By collaborating with clinicians, pharmacists, clinical laboratory technicians, and researchers from various backgrounds, the group formulates research plans, creates disease model mice using genome editing, and provides technical support for mouse analysis. In addition to offering this foundational research infrastructure, the members also verify the functions of multiple gene mutations in hereditary diseases as part of their individual research projects.
Genetic Variation Verification Group Results
Main Results
- 日本人において多型が多くみられるアレルギー疾患感受性に関わるゲノム変異マウスを作製
- 緑内障、先天性代謝異常症、血小板減少症における原因遺伝子の変異マウスを作製
